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Chiropractic Research Review

Prescription Medications May Contribute to Obesity

While the escalating problem of obesity may be attributed to a number of different factors, including changes in diet, reduced physical activity, and smoking cessation, the authors of this article suggest that a relationship between substantial weight gain and the use of prescription medications may exist.

The article details the results of an extensive literature search on the influence of prescription medications on weight gain.

Included are case reports and a list, by class of drug and indication, of commonly prescribed medications known to contribute to weight gain, including:

* insulin;
* calcium channel blockers for hypertension;
* medications for gastrointestinal disorders;
* psychoactive medications;
* anticonvulsant medications; and
* steroid hormones.

The authors conclude that medication-related increases in appetite and body weight are under-recognized and can cause noncompliance with pharmacotherapy. They suggest that health care professionals who are aware of the known effects of medications can better inform their patients how to avoid weight gain and other unnecessary complications.

Take Note: The authors list a number of specific drugs that may cause weight gain. We listed categories only; some drugs in these categories may not contribute to weight gain. For an exhaustive list of specific drugs, see the full text of the original article.

Cheskin LJ, Bartlett SJ, Zayas R, et al. Prescription medications: a modifiable contributor to obesity. Southern Medical Journal, Sept. 1999:92(9), pp898-904.

Chiropractic Research Review

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