Dynamic Chiropractic

Dynamic Chiropractic Facebook Twitter
Dynamic Chiropractic
Find
Advanced Search
Wellness Blog
Dynamic Chiropractic PracticeINSIGHTS
Current Graphic
Facebook
Dynamic Chiropractic – November 4, 2008, Vol. 26, Issue 23
Dynamic Chiropractic
Printer Friendly Email a Friend PDF RSS Feed
Share |
Dynamic Chiropractic

dynamicchiropractic.com >> Headaches & Migraines

Imitrex (Sumatriptan Succinate)

By Daniel Hough, DC

The first article in this series, "Fosamax," appeared in the Aug. 26 issue.


These days, we are bombarded with advertisements for prescription drugs. Many of our patients are taking these drugs.

According to Fortune magazine, total 2007 revenue for the pharmaceutical industry was more than half a trillion dollars and its profits were more than $79 billion. As chiropractors, we need to be informed about these prescription drugs so we can educate our patients about their effects, side effects and dangers, as well as suggest safer alternatives when appropriate. (Don't count on their medical doctor or pharmacist to fully inform them.)

Imitrex is sold for the relief of the symptoms of migraine headaches. It doesn't cure anything; it is only palliative. Imitrex is available in three forms: injection, nasal spray or tablet. It is known as a 5-HT agonist and is a powerful vasoconstrictor. Other drugs in the same class as Imitrex include Amerge, Maxalt and Zomig. A generic version is not yet available.

Imitrex is manufactured by GlaxoSmithKline. In 2006, GSK's total sales from pharmaceuticals were approximately $45 billion.1 On Sept. 2, 2008, Mr. Dan Troy was appointed senior vice president and general council at Glaxo- SmithKline. Troy formerly served as chief council for the U.S. Food and Drug Administration. It appears GlaxoSmithKline and the FDA have a rather cozy relationship.2

CVS Pharmacy in Bozeman, Mont., where I practice, charges $28.89 for a single 50 mg tablet of Imitrex. Patients are advised to take up to 100 mg Imitrex per day. The Physicians' Desk Reference lists more than 100 adverse side effects from taking sumatriptan succinate, including: muscle weakness, serious heart problems, seizure, severe allergic reactions, anxiety, backflow of stomach contents, confusion, depression, joint pain, muscle pain, and, ironically, headaches.3

Vascular headaches are caused by the compromise of the postganglionic sympathetic nerves above the superior sympathetic ganglion. These nerves control, among other functions, blood vessel diameter in the cranium and function of the dilator pupilae muscles, which dilate the pupils of the eyes.

Subluxation of the atlas/occipital articulation compromises those nerves, causing them to fire.  This then causes vasoconstriction of the blood vessels in the head and dilation of the pupils, which explains the photophobia many migraine sufferers experience. The vasoconstriction eventually leads to hypoxia of the tissues surrounding the brain. Hypoxic tissues become acidic and release substance P, bradykinins and histamine, which causes vasodilatation and increased capillary permeability. The tissues in the skull are then flooded with fluid, causing the vascular headache.

Vascular headaches are divided into several types: common migraine, classic migraine, complicated migraine and cluster headaches. The etiology and chiropractic treatment is the same for all types.4 Treatment is safe and simple: adjustment of the C0/C1 cervical joint usually stops these headaches within minutes. Sometimes ergonomic changes are appropriate to avoid re-subluxation of the upper cervical spine. Over the years, I have noticed that patients who have recurring migraines are many times suffering from subclinical hypothyroidism. Referral for treatment of hypothyroidism with a preparation containing both thyroxine and triiodothyronine, if lab tests (T3 Free) so indicate, will allow the adjustment to hold and keep the headaches at bay with only an occasional adjustment.5

References

  1. GlaxoSmithKline. www.gsk.com/investors/presentations/2007/roundtable07/viehbacher roundtable07.
  2. www.biohealthinvestor.com/tag/glaxosmithkline.
  3. Sifton DW, et al. The PDR Pocket Guide to Prescription Drugs, 5th Edition. New York: Simon and Schuster, pp. 599-604.
  4. Hough D. "Cause and Treatment of Migraine Headaches." Dynamic Chiropractic, Nov. 1, 1999;17(23).
  5. Hough D. "What Every Chiropractor (and MD) Should Know About the Thyroid." Dynamic Chiropractic, April 7, 2003;21(8)

Dr. Daniel Hough is a 1991 graduate of Western States Chiropractic College. A former member of the Montana Chiropractic Association Ethics Committee, he practices in Bozeman, Mont.

Dynamic Chiropractic

Dynamic Chiropractic
Printer Friendly Email a Friend PDF RSS Feed
Share |
Dynamic Chiropractic
Dynamic Chiropractic
Join the conversation
Comments are encouraged, but you must follow our User Agreement
Keep it civil and stay on topic. No profanity, vulgar, racist or hateful comments or personal attacks. Anyone who chooses to exercise poor judgement will be blocked. By posting your comment, you agree to allow MPA Media the right to republish your name and comment in additional MPA Media publications without any notification or payment.
comments powered by Disqus
Dynamic Chiropractic
Have you ever contacted a local employer about the possibility of directing their corporate wellness program?
Yes, contacted
Yes, directing
Thinking about it
No

Sign Up for Our Webinars
Receive Advanced Notice of Future Webinars

 


Generic Viagra Lowest Prices Pfizer Drugs Viagra No Prescription Order Viagra Online Viagra Non Prescription Deal Sale Prescription Viagra Uk Online Levitra Reviews Viagra Oysters In Australia Viagra Price Australia Cialis Pill Color Generic Viagra Canada Buy Cheap Viagra Viagra Katelaris P Viagra Australia Cheap Levitra Prescription Or Not Viagra Levitra Usual Dosage Buy Tadalafil Cialis Online Viagra And Daibetes Viagra Tablets Uk Viagra Online From Us Pharmacys Generic Money Viagra Cialis And Priligy Next Dat Delivery Generic Viagra Vigora 5000 Effect Viagra Drug Interactions Online Levitra Tablet Viagra Buy Online Levitra Drug Interaction Walgreen Viagra Per Pill Viagra Online Gr 4.26 Buy Cialis Lowest Price Viagra Online Cheap Mexico Viagra Buying Free Sale Viagra Cheap Kamagra Viagra Buy Generic Online Viagra Viagra Online Sales Brand Viagra For Get Viagra Without Prescription Viagra Side Effects Blood Pressure Cialis For Sale In Us Australia Viagra Online Cialis Cheap Visa Auk Cialis Sales Bravejournal Buy Levitra Member Levitra Buy Online Find Cheap Cialis Vardenafil 20 Mg Hcl